If something is the issue, it is the thing you consider to be the most important part of a situation or discussion.
要点 • I was earning a lot of money, but that was not the issue.
If you issue a statement or a warning, you make it known formally or publicly.
发表 (声明); 发出 (警告) • Last night he issued a statement denying the allegations. 昨天晚上,他发表了一项声明否认那些说法。